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The Most Affordable HiFi Genome Yet

New SPRQ-Nx chemistry reduces costs and adds multiomic capabilities. Be among the first to experience richer data, lower price per genome, and flexibility.

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Get ready for Beyond the Bench

A new kind of science series is coming in January. Step inside the lives of leading genomicists for off-the-clock conversations in the places that keep them grounded outside the lab. Immersive, bingeable, and worth catching on premiere day.

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Apply now for the 2025 Immunology and Immunotherapy SMRT Grant program

Could your research benefit from highly accurate long-read sequencing? Apply for this immunology and immunotherapy SMRT Grant! With highly accurate long reads, known as HiFi reads, you can elevate your research to the next level.

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Sequencing methods for solutions that matter

Our technology provides the most comprehensive view of genomes, transcriptomes, and epigenomes.

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Whole genome sequencing

Achieve the highest consensus accuracy and uniform coverage for reference quality genomes in humans, plants, animals, and microbes.

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Targeted sequencing

Accurately detect and uncover all variant types even in hard-to-reach regions of the genome.

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Epigenetics

Explore how epigenetic changes affect gene expression, host-pathogen interactions, environmental response, and more.

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RNA sequencing

Discover new genes, transcripts, and alternative splicing events with a complete view of transcript isoform diversity.

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Accelerate your research

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Application note

Kinnex full-length RNA Kit for isoform sequencing

The Kinnex full-length RNA kit for bulk RNA sequencing produces 15 million reads and 40 million reads per SMRT Cell on Sequel II and Revio systems. This represents a 15-fold throughput increase on Revio with Kinnex.

See how

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A roadmap to expand PureTarget repeat expansion and carrier panels, enabling high-throughput clinical research solutions

Introducing two new panels – an updated repeat expansion panel and a new carrier screening panel – plus a 96-plex automation kit and a full software pipeline for carrier screening. Together, these tools streamline legacy assays into one efficient, high-throughput workflow to provide more value for key applications in clinical and diagnostic research and carrier screenin

Learn more

Sequencing 101: Long-read sequencing

Long-read sequencing technologies are quickly becoming the new gold standard in genomics research, and HiFi sequencing is at the forefront. This article provides an introductory look at what long-read sequencing is, and explores topics the advantages, applications of using long-read sequencing in your research.

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What can you do with a Revio system?

Access more information at reduced cost and higher throughput with Revio long-read sequencing.

See what you can get

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10,000+ articles, reports, papers, and videos

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Recent press

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  • PacBio to Participate in the Piper Sandler 37th Annual Healthcare Conference
    November 28, 2025 | GLOBE NEWSWIRE

  • PacBio to Present at Upcoming Investor Conferences
    November 13, 2025 | GLOBE NEWSWIRE

  • PacBio Announces Third Quarter 2025 Financial Results
    November 05, 2025 | GLOBE NEWSWIRE

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Recent articles

  • Powered by PacBio:
    Selected publications from November 2025
    December 04, 2025

  • How long-read sequencing informs the future of food from genome to table
    November 26, 2025

  • Publication spotlight:
    First major study from the HiFi Solves EMEA consortium showcases the potential clinical power of a HiFi genome
    November 24, 2025

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