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HiFi software downloads

The PacBio SMRT Analysis software suite is designed for use with HiFi sequencing data. You can analyze, visualize, and manage your data through an intuitive GUI or command-line interface. You can also integrate SMRT Analysis in your existing data workflow through the extensive set of APIs provided.

RECOMMENDED SMRT LINK SOFTWARE VERSIONS

Vega system Revio system Sequel II/IIe systems
SMRT Link v25.1 SMRT Link v25.1 SMRT Link v13.1

DOWNLOAD SMRT LINK V25.1

Recommended for the Revio system and required for the Vega system Download SMRT Link v25.1

SMRT Link v25.1 is strongly recommended for the Revio system and required for the Vega system. SMRT Link v25.1 is required to use SPRQ chemistry on the Revio system.

Note: If your fleet includes a Sequel II/IIe system, you’ll also need an installation of SMRT Link v13.1.

Software version support period

  • Release date: December 2024
  • End of support date: December 2026

DOWNLOAD SMRT LINK V13.1

Required for long-term support on the Sequel Il/lle systems Download SMRT Link v13.1 (Sequel II/IIe)    Download SMRT Link v13.1 (Revio)

SMRT Link v13.1 is required for long-term support on the Sequel II/IIe system. While SMRT Link v13.1 is compatible with the Revio system, we recommend Revio users upgrade to v25.1.

Note: Users with both Sequel II/IIe and Revio systems should use the Revio download.

SMRT Link v13.1 developer documentation

Software version support period

  • Release date: June 2024
  • End of support date (Sequel II/lle systems): Long-term support
  • End of support (Revio system): June 2026

Legacy SMRT Link versions

Contact PacBio support for assistance with downloading legacy SMRT Link versions.

SMRT Link v13.0 documentation

Release documentation

Developer documentation

Software version support period

  • Release date: March 2024
  • End of support date: March 2026

Contact PacBio support for assistance with downloading legacy SMRT Link versions.

SMRT Link v12.0 documentation

Release documentation

Developer documentation

Software version support period

  • Release date: March 2023
  • End of support date: March 2025

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