Olga Troyanskaya, PhD

Dr. Troyanskaya joined our scientific advisory board in 2023. Olga Troyanskaya is a Professor at the Lewis-Sigler Institute for Integrative Genomics and the Department of Computer Science at Princeton University and the Deputy Director for Genomics at the Flatiron Institute, Simons Foundation. She also directs Princeton Precision Health, an initiative that uses AI and data science to fundamentally transform human health by integrating research from a breadth of fields — from molecular to social and environmental — with the goal of enacting smart policy and evidence-based clinical practice. Dr. Troyanskaya’s lab builds AI and modeling techniques to decode genomes and understand cellular specificity, genotype-phenotype relationships, and biology underlying complex diseases.

Her group pioneered the use of functional networks to map tissue and cellular specificity to study pathway dysregulation in disease and of deep learning models to study regulatory genomes, enabling study of transcriptional and post-transcriptional variants and their role in cellular function, evolution, and diseases.  Through developing AI-based integrative approaches, her lab focuses on studying the non-coding genome and modeling of complex molecular-level changes captured via diverse multi-omics techniques, including in specific clinical, treatment, and environmental contexts, enabling systems-level molecular views of human health and disease.

Dr. Troyanskaya has democratized the use of these machine learning approaches with interactive, public interfaces for the biomedical community. Dr. Troyanskaya received her PhD from Stanford University in 2003, is a member of the National Advisory Council for Human Genome Research, and is an Association for Computing Machinery fellow. She is a recipient of the Sloan Research Fellowship, the National Science Foundation CAREER award, the Ira Herskowitz Award from The Genetics Society of America, and the Overton Prize in computational biology.