Detection of translocatable units in a blaCTX-M-15 extended-spectrum ß-lactamase-producing ST131 Escherichia coli isolate using a hybrid sequencing approach.

Authors: Ghosh, Hiren and Doijad, Swapnil and Bunk, Boyke and Falgenhauer, Linda and Yao, Yancheng and Spröer, Cathrin and Gentil, Katrin and Schmiedel, Judith and Imirzalioglu, Can and Overmann, Jörg and Chakraborty, Trinad

Sir,Escherichia coli sequence type 131 (ST131) producing CTX- M-type [3-lactamases are the most common extended-spectrum [3-lactamase (ESBL)-producing strains and are of high virulence potential. In particular, the blal-;X.M.[5 gene is often encoded on a conjugative plasmid and less frequently on the chromo- some. The presence of identical bluCTX.M.[5 alleles on both the chromosome and on a plasmid in the same strain has been reported [1], suggesting transfer ofthese genes between these two locations.

Journal: International journal of antimicrobial agents
DOI: 10.1016/j.ijantimicag.2016.01.003
Year: 2016

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