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HiFi software downloads

The PacBio SMRT Analysis software suite is designed for use with HiFi sequencing data. You can analyze, visualize, and manage your data through an intuitive GUI or command-line interface. You can also integrate SMRT Analysis in your existing data workflow through the extensive set of APIs provided.

RECOMMENDED SMRT LINK SOFTWARE VERSIONS

Vega system Revio system Sequel II/IIe systems
SMRT Link v25.2 SMRT Link v25.2 SMRT Link v13.1

Download SMRT LINK V25.2

Recommended for the Revio system and Vega system
SMRT Link v25.2

SMRT Link v25.2 is strongly recommended for the Revio system and the Vega system. SMRT Link v25.2 is required for use with the Vega v1.1 instrument software update.  Contact tech support to access SMRT Link Cloud.

Note: If your fleet includes a Sequel II/IIe system, you’ll also need an installation of SMRT Link v13.1.

SMRT Link v25.2 release documentation

Software version support period

Release date: March 2025
End of support date: March 2027

SMRT Link Cloud FAQs

For more detailed questions and answers about SMRT Link Cloud, visit Support FAQs

Download SMRT Link v13.1

Required for long-term support on the Sequel II/IIe systems SMRT Link v13.1 (Sequel II/IIe systems) SMRT Link v13.1 (Revio systems)

SMRT Link v13.1 is required for long-term support on the Sequel II/IIe systems. While SMRT Link v13.1 is compatible with the Revio system, we recommend Revio users upgrade to v25.2.

Note: users with both Sequel II/IIe and Revio systems should use the Revio download.

SMRT Link v13.1 release documentation

Software version support period

  • Release date: June 2024
  • End of support date (Sequel II/IIe systems): Long-term support
  • End of support (Revio system): June 2026

Previous SMRT Link versions

SMRT Link v25.1 or above is required to use SPRQ chemistry on the Revio system.

Download SMRT Link v25.1

  • Release date: December 2024
  • End of support date: December 2026

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If you have a question, need to check the status of an order, or are interested in purchasing an instrument, we're here to help.